I've played with Podcast Generator before, but haven't stuck with it. Not because there's anything wrong with it, but because I was with a host that took care of my feed generation and all.
Podcast Generator is a free PHP script released under GPL which allows to upload media files via a web form and automatically create podcast rss 2.0 w3c-compliant feeds. It also features a web administration and a dynamic web page displaying new podcasts.
If you're in the business of hosting your podcasts, this baby might take the pain out of hand-rolling your own XML files for your feed.
